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75 Y/M with altered sensorium

 THIS IS AN ONLINE E LOG BOOK TO DISCUSS OUR PATIENT'S DE - IDENTIFIED HEALTH DATA SHARED AFTER TAKING HIS / HER /GUARDIAN'S SIGNED INFORMED CONSENT .HERE WE DISCUSS OUR INDIVIDUAL PATIENT'S PROBLEMS THROUGH SERIES OF INPUTS FROM AVAILABLE GLOBAL ONLINE COMMUNITY OF EXPERTS WITH AN AIM TO SOLVE THOSE CLINICAL PROBLEMS WITH COLLECTIVE CURRENT BEST EVIDENCE BASED INPUT.    


This E blog also reflects my patient centered online learning portfolio and your valuable inputs on the comment box is welcome.


I have been given this case to solve in an attempt to understand the topic of " patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with diagnosis and treatment plan   


2-08-2022

A 75 year old male came with complaints of 

*Fever since 10 days 

*Altered sensorium since 5 days  


HOPI:

Patient was apparently asymptomatic 10 days back and then developed fever which was high grade not associated with chills and rigor. Then he developed altered sensorium since 5 days he was not able to recognise his family members.


PAST HISTORY:

Not a K/C/O DM, HTN, TB,EPILEPSY, ASTHMA

Has hypo-pigmented patches on b/l lower limbs and b/l nipples since 6 years using herbal medication regularly, itching is present.


PERSONAL HISTORY:

He is Married

He consumes 

Mixed diet 

sleep is adequate 

Appetite normal

bowel and bladder movements are regular

He Consumes Alcohol twice a week (90ml) since 50 years presently abstinent since 15 days 

He smokes beedi 1-2 packs/day since 55 years 


FAMILY HISTORY: No similar complaints in the family.




GENERAL EXAMINATION:
Patient is conscious ,non-cooperative, not oriented to time, place and person.

Thinly built and nourished.

VITALS:

BP: 120/70mmhg
PR: 90bpm
RR: 20cpm
Temp: 100f

SYSTEMIC EXAMINATION:

RS:
Inspection : barrel shape 
Decreased breath sounds on right side 
Diffuse expiratory wheeze
CVS: s1,s2 no added sounds
P/A: not tender

Pt is altered
GCS - E3V1M6 
Speech - making incomprensible sounds 
Pupils:NSRL
Motor 
Power : Not moving his left upper limb and lower limb as actively as right side

Tone : Normal
Reflexes :   B T S A K P 
                 R: - - - - - Flexion 
                 L : - - - - - Flexion 
Neck rigidity : Present 
Kerning's : Positive 
Brudzski : Negative

PROVISIONAL DIAGNOSIS: 

ALTERED SENSORIUM UNDER EVALUATION 

INVESTIGATIONS:


On Day1 

ABG: Day 1 at 10:43pm


ABG: Day 1 at 11:51pm











LP PROCEDURE 1:
https://youtu.be/y1S-wxUALbs

2D ECHO:
https://youtu.be/oH2VtYcXrz4

TREATMENT:
1.INJ.CEFTRIAXONE 2gm IV/STAT then 1gm IV/BD
2.INJ.IVF DNS 50ml/hr
3.INJ.PANTOP 40mg IV/OD
4.INJ.ZOFER 4mg IV/SOS
5.INJ.OPTINEURON 1AMP IN 100ml NS IV/OD
6.MONITOR VITALS EVERY 6th hrly
7.GRBS MONITORING EVERY 4th 


Day 2

S: fever since 10 days and altered sensorium since 5 days
Presently altered sensorium 

O: pt is conscious,uncooperative,not oriented to time,place and person.
BP: 120/70mmhg
PR: 90bpm
RR: 20cpm
Temp: 98.6f

SYSTEMIC EXAMINATION:

RS:
Inspection : barrel shape 
Decreased breath sounds on right side 
Diffuse expiratory wheeze

CVS: s1,s2 no added sounds

P/A: not tender

CNS:
Pt is altered
GCS - E3V1M6 
Speech - making incomprensible sounds 
Motor 
Power : Not moving his left upper limb and lower limb as actively as right side
Tone : Normal
Reflexes : B T S A K P 
           R: - - - - - Flexion 
           L : - - - - - Flexion 
Neck rigidity : Present 
Kerning's : Positive 
Brudzski : Negative

A: ?Altered sensorium under evaluation
?Alcohol withdrawal syndrome 

P:
1.INJ.CEFTRIAXONE 2gm IV/STAT then 1gm IV/BD
2.INJ.IVF DNS 50ml/hr
3.INJ.PANTOP 40mg IV/OD
4.INJ.ZOFER 4mg IV/SOS
5.INJ.OPTINEURON 1AMP IN 100ml NS IV/OD
6.MONITOR VITALS EVERY 6th hrly
7.GRBS MONITORING EVERY 4th hrly

INVESTIGATIONS:

ABG: Day 2 at 6:17 am








Plan: Patient intubated on ACMV VC MODE as he was hypoxic Post Intubation Ventilator Settings : 
RR - 16
Fio2 - 40
PEEP - 5 
TV - 400

Post Intubation Vitals :
Pupils - B/L Fixed Pin point Pupils 
BP - 100/70mmHg 
PR - 116/Min 
RR - 22/Min 
Spo2 - 100%

Midaz Infusio - 5ml/hr
Atracurium Infusion - 10ml/hr

ABG:Day 2 at 9:50pm



Day 3

S:pt is on mechanical ventilator and sedation 

O: pt on SIMV VC mode
RR TOTAL: 29
RR:20
Fio2:30%
PEEP: 5 cm of H2O
TV:400

VITALS:
BP: 110/70mmhg
PR: 82bpm
RR: 16cpm
Temp: 98.5f

SYSTEMIC EXAMINATION:
CVS: s1,s2 no added sounds
P/A: not tender

A: Altered sensorium secondary to meningitis with type 1 respiratory failure with acute exacerbation of COPD.

P:
TREATMENT:
1.INJ.CEFTRIAXONE 2gm IV/STAT then 1gm IV/BD
2.RT FEEDS 100ml milk 4th hrly, 50ml water 2nd hourly 
3.INJ.PANTOP 40mg IV/OD
4.INJ.ZOFER 4mg IV/SOS
5.INJ.OPTINEURON 1AMP IN 100ml NS IV/OD
6.Inj.NEOMOL IV if TEMP>102f sos
7.GRBS MONITORING EVERY 4th hrly
8.Inj.MIDAZ 5ml/hr
9.Tab. Azithromycin 500mg PO/OD

ABG: Day 3 at 5:24 Am



CT scan




Chest X ray


ABG: Day 3 at 7:20 Am





Day 3 At 9:30 am 
Pt was able to breath on its own so the changes were done to SIMV -VC Mode 
RR Total - 29
RR - 16
Fio2 - 30 
PEEP - 5 
VT - 400

Vitals - 
BP - 100/80
RR - 38/min
HR - 108/min
Spo2 - 97

ABG: Day 3 at 12:20pm




On Day 4

S:pt is on mechanical ventilator and sedation 

O: pt on SIMV VC mode
RR TOTAL: 29
RR:20
Fio2:30%
PEEP: 5 cm of H2O
TV:400

VITALS:
BP: 110/70mmhg
PR: 97bpm
RR: 16cpm
Temp: 97.6f

SYSTEMIC EXAMINATION:
CVS: s1,s2 no added sounds
P/A: not tender

A: Altered sensorium secondary to meningitis with type 1 respiratory failure with acute exacerbation of COPD.

P:
TREATMENT:
1.INJ.CEFTRIAXONE 2gm IV/STAT then 1gm IV/BD
2.RT FEEDS 100ml milk 4th hrly, 50ml water 2nd hourly 
3.INJ.PANTOP 40mg IV/OD
4.INJ.ZOFER 4mg IV/SOS
5.INJ.OPTINEURON 1AMP IN 100ml NS IV/OD
6.Inj.NEOMOL IV if TEMP>102f sos
7.GRBS MONITORING EVERY 4th hrly







Chest X Ray



ABG: Day 4 at 1:36pm






ABG: Day 4 at 10:36pm

ABG: Day 5 at 6:30am


Day 5

S:pt is on mechanical ventilator and sedation 

O: pt on SIMV VC mode
RR TOTAL: 34
RR:16
Fio2:21%
PEEP: 5 cm of H2O
TV:400

VITALS:
BP: 130/70mmhg
PR: 122bpm
RR: 20cpm
Temp: 100.8f
SpO2: 97%
GRBS: 327 mg/dl

SYSTEMIC EXAMINATION:
CVS: s1,s2 no added sounds
P/A: not tender
CNS:
Doll’s eye reflex +
Pt is unresponsive
GCS - E1VTM1
Pupils:B/L equal constricted and reacting to light.
                          R L
Corneal + +
Conjunctival. +. +
Tone : Hypotonia
Reflexes : B T S A K P 
           R: - - - - - Flexion 
           L : - + - - - Flexion



A: Altered sensorium secondary to meningitis with type 1 respiratory failure with acute exacerbation of COPD.

P:
TREATMENT:
1.INJ.CEFTRIAXONE 2gm IV/STAT then 1gm IV/BD
2.RT FEEDS 100ml milk 4th hrly, 50ml water 2nd hourly 
3.INJ.PANTOP 40mg IV/OD
4.INJ.ZOFER 4mg IV/SOS
5.INJ.Dexamethasone 4mg BD
6.Inj.NEOMOL IV if TEMP>102f sos
7.GRBS MONITORING EVERY 4th hrly
8.INJ.Clexane 40mg S/C OD
9.Tab. Azithromycin 500mg PO/OD
10.NEB BUDECORT 12th hrly DUOLINE 8th hourly 
11.Monitor vitals





Day 5 at 3:50pm


Day 6

S:pt removed from ventilation and was put on T. Piece since today morning 7.30 am 

O:
Pt conscious 
GCS:E4VTM4
spontaneous eye opening + 
Spontaneous breathing +

VITALS:
BP: 120/70mmhg
PR: 137bpm
RR: 30cpm
Temp: 101.3f
SpO2: 98%
GRBS: 197 mg/dl at 8:00am

SYSTEMIC EXAMINATION:
CVS: s1,s2 no added sounds
P/A: not tender,Soft

A: fever with Altered sensorium secondary to meningitis with type 1 respiratory failure with acute exacerbation of COPD.

P:
Plan to extubate



ABG: Day 6 at 6:20am

ABG: Day 6 at 9:30am

Culture 




Day 7

S:pt extubated yesterday at 4:00pm
Bed sores at sacral area

O:
Pt conscious 
GCS: E4V5M3
spontaneous eye opening + 
Spontaneous breathing +

VITALS:
BP: 120/70mmhg
PR: 98bpm
RR: 33cpm
Temp: 98.7f
SpO2: 98%
GRBS: 335 mg/dl at 8:00am

CSF reports awaiting 
URINE CULTURE: 
isolated E.coli sensitive to :
Nitrofurantoin
Gentamicin 
Cotrimoxazole
Fosfomycin
Amikacin
Tazobactum
Clavulenic acid
Meropenam

SYSTEMIC EXAMINATION:
CVS: s1,s2 no added sounds
P/A: not tender,Soft
RS:BAE+

A: fever with Altered sensorium secondary to meningitis with type 1 respiratory failure with acute exacerbation of COPD, BED SORES + (sacral area Grade II)

P:
RT FEEDS 100ml milk 4th hrly, 50ml water 2nd hrly
Inj.PAN 40mg/IV/OD
Inj.Zofer 4mg/IV/SOS
Inj.Neomol 1gm/IV/TEMP>102f
Neb with budecort 12th hrly, duoline 8th hourly
Frequent change of position every 2nd hrly

Procedures: LP Procedure done at 8:00am today


LP PROCEDURE 2:https://youtu.be/pxf9FxhtPXA






ABG:Day 7 at 6:00pm












Day 8

S:
Bed sores at sacral area

O:
Pt conscious 
GCS: E4V5M3
spontaneous eye opening + 
Spontaneous breathing +

VITALS:
BP: 120/70mmhg
PR: 92bpm
RR: 22cpm
Temp: 98.5f
GRBS: 345mg/dl at 8:00am

SYSTEMIC EXAMINATION:
CVS: s1,s2 no added sounds
P/A: not tender,Soft
RS:BAE+

A: fever with Altered sensorium secondary to meningitis with type 1 respiratory failure with acute exacerbation of COPD, BED SORES + (sacral area Grade II)

P:
RT FEEDS 100ml milk 4th hrly, 50ml water 2nd hrly
Inj.PAN 40mg/IV/OD
Inj.Zofer 4mg/IV/SOS
Inj.Neomol 1gm/IV/TEMP>102f
Neb with budecort 12th hrly, duoline 8th hourly
Frequent change of position every 2nd hrly

ABG: day 8 at 6:00am





Day 9

S:
Bed sores at sacral area

O:
Pt conscious 
GCS: E4V5M3
spontaneous eye opening + 
Spontaneous breathing +

VITALS:
BP: 120/70mmhg
PR: 92bpm
RR: 22cpm
Temp: 98.5f
GRBS: 345mg/dl at 8:00am

SYSTEMIC EXAMINATION:
CVS: s1,s2 no added sounds
P/A: not tender,Soft
RS:BAE+

A: fever with Altered sensorium secondary to meningitis with type 1 respiratory failure with acute exacerbation of COPD, BED SORES + (sacral area Grade II)

P:
RT FEEDS 100ml milk 4th hrly, 50ml water 2nd hrly
Inj.PAN 40mg/IV/OD
Inj.Zofer 4mg/IV/SOS
Inj.Neomol 1gm/IV/TEMP>102f
Neb with budecort 12th hrly, duoline 8th hourly
Frequent change of position every 2nd hrly









ABG: day 9 at 8:00am


Day 10

S:
Bed sores at sacral area
Dressing is done

O:
Pt conscious 
GCS:E4V4M3
VITALS:
BP: 110/70mmhg
PR: 96bpm
RR: 30cpm
Temp: 98.5f
GRBS: 195mg/dl at 8:00am

SYSTEMIC EXAMINATION:
CVS: s1,s2 no added sounds
P/A: not tender,Soft
RS:BAE+

A: fever with Altered sensorium secondary to meningitis with type 1 respiratory failure with acute exacerbation of COPD, BED SORES + (sacral area Grade II)

P:
Mobilise him with support 
RT FEEDS 100ml milk 4th hrly, 50ml water 2nd hrly
Inj.PAN 40mg/IV/OD
Inj.Zofer 4mg/IV/SOS
Inj.Neomol 1gm/IV/TEMP>102f
Neb with budecort 12th hrly, duoline 8th hourly
Frequent change of position every 2nd hrly

Day 11

S:
Bed sores at sacral area grade 2-3 

O:
Pt conscious 
GCS:E4M6V3
VITALS:
BP: 110/70mmhg
PR: 94bpm
RR: 26cpm
Temp: 98F
GRBS: 235mg/dl at 8:00am

SYSTEMIC EXAMINATION:
CVS: s1,s2 no added sounds
P/A: not tender,Soft
RS:BAE+

A: fever with Altered sensorium secondary to meningitis with type 1 respiratory failure with acute exacerbation of COPD, BED SORES + (sacral area Grade II)

P:
Mobilise him with support 
RT FEEDS 100ml milk 4th hrly, 50ml water 2nd hrly
Inj.PAN 40mg/IV/OD
Inj.Zofer 4mg/IV/SOS
Inj.Neomol 1gm/IV/TEMP>102f
Neb with budecort 12th hrly, duoline 8th hourly
Frequent change of position every 2nd hrly








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